A statistical framework for testing functional categories in microarray data
نویسندگان
چکیده
منابع مشابه
A Statistical Framework for Testing Functional Categories in Microarray Data
Ready access to emerging databases of gene annotation and functional pathways has shifted assessments of differential expression in DNA microarray studies from single genes to groups of genes with shared biological function. This paper takes a critical look at existing methods for assessing the differential expression of a group of genes (functional category), and provides some suggestions for ...
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15 صفحه اولThe False Discovery Rate in Simultaneous Fisher and Adjusted Permutation Hypothesis Testing on Microarray Data
Background and Objectives: In recent years, new technologies have led to produce a large amount of data and in the field of biology, microarray technology has also dramatically developed. Meanwhile, the Fisher test is used to compare the control group with two or more experimental groups and also to detect the differentially expressed genes. In this study, the false discovery rate was investiga...
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ژورنال
عنوان ژورنال: The Annals of Applied Statistics
سال: 2008
ISSN: 1932-6157
DOI: 10.1214/07-aoas146